5-alpha-reductase inhibitors are a group of medicines that block the action of 5-alpha-reductase, the enzyme that converts testosterone into dihydrotestosterone. This results in increased levels of testosterone and decreased levels of dihydrotestosterone; an overabundance of dihydrotestosterone has been implicated in benign prostatic hyperplasia (BPH) and prostate cancer. The scalp of men with androgenetic alopecia (male-pattern baldness) has also been found to contain increased amounts of dihydrotestosterone and miniaturized hair follicles compared with men who have a lot of hair.
Currently, two 5-alpha-reductase inhibitors are available, finasteride and dutasteride. The 5-alpha-reductase enzyme exists in two forms: type 1 and type 2. Finasteride inhibits type 2 only, whereas dutasteride inhibits both. Although dutasteride provides greater suppression of dihydrotestosterone, it is not known if this provides a significant advantage clinically. Rates of side effects such as impotence, decreased libido, ejaculation disorder, and gynecomastia are similar.
5-alpha-reductase inhibitors may be used in the treatment of benign prostatic hyperplasia (enlarged prostate gland) and male-pattern hair loss (androgenic alopecia). They are not approved for the prevention of prostate cancer.
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Source:drugs.com
Avodart
AVODART is a medication used to treat symptoms of an enlarged prostate gland, also known as benign prostatic hyperplasia (BPH). It works by reducing the size of the prostate gland, improving urinary flow, and reducing the risk of urinary retention and the need for surgery. AVODART is a prescription medication and should be taken as directed by a healthcare professional.
Dutasteride is a medication used to treat symptoms of an enlarged prostate gland, also known as benign prostatic hyperplasia (BPH). It works by reducing the size of the prostate gland, which helps to relieve urinary problems such as frequent urination, difficulty starting and stopping urination, and weak urine flow. Dutasteride is typically taken orally in the form of a capsule and is available by prescription only. It is important to follow the dosage instructions provided by a healthcare professional and to discuss any potential side effects or interactions with other medications.
Dutasteride-tamsulosin is a combination medication used to treat symptoms of an enlarged prostate gland, also known as benign prostatic hyperplasia (BPH). It contains two active ingredients, dutasteride and tamsulosin, which work together to reduce the size of the prostate gland and improve urinary flow. This medication is typically prescribed for men who have moderate to severe symptoms of BPH and can help alleviate symptoms such as frequent urination, difficulty starting and maintaining urination, and weak urine flow. Dutasteride-tamsulosin is available in capsule form and should be taken as directed by a healthcare professional.
Finasteride is a medication used to treat male pattern hair loss and benign prostatic hyperplasia (enlarged prostate). It works by inhibiting the conversion of testosterone to dihydrotestosterone (DHT), a hormone that contributes to hair loss and prostate enlargement. This medication is available in tablet form and is typically taken once daily. It is important to note that finasteride is only approved for use in men and should not be used by women or children. Common side effects may include decreased libido, erectile dysfunction, and breast tenderness.
Propecia is a medication used to treat male pattern hair loss. It works by inhibiting the conversion of testosterone to dihydrotestosterone (DHT), which is responsible for hair loss in men. Propecia is taken orally and is typically prescribed for long-term use to maintain hair growth. It has been shown to be effective in slowing down hair loss and promoting hair regrowth in many men. However, it may take several months of continuous use before noticeable results are seen. Propecia is only approved for use in men and should not be taken by women or children.
