Catecholamines include adrenaline, noradrenaline and dopamine. They are physiologically important neurotransmitters, as part of the sympathetic and central nervous systems. Catecholamines act on both the alpha and beta adrenergic receptors. Catecholamines are released in times of stress. They make your heart beat faster with greater force and narrow the blood vessels, causing a rise in blood pressure.
The beta1 effects of catecholamine on the heart are due to an increase in intracellular concentration of cyclic-AMP. Cyclic-AMP activates protein kinase A, which phosphorylates sites on calcium channels, including alpha1-subunits.
This increases the probability that the channels will open, increasing inward calcium ion current and therefore the force of cardiac contraction. It also increases the calcium ion capture by the sarcoplasmic reticulum, increasing the amount of calcium stored intracellularly available for release by action potential. So the net result of catecholamine action is to elevate and steepen the ventricular function curve.
The increase in heart rate results in an increased slope of pacemaker potential owing to a shift in the voltage-dependence of the conductance's underlying the pacemaker currents so that they are switched on and reach firing threshold, earlier.
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Source:drugs.com
Epinephrine
Epinephrine is a hormone and neurotransmitter that is produced by the adrenal glands. It plays a crucial role in the body's response to stress and emergency situations. Epinephrine increases heart rate, blood pressure, and blood sugar levels, preparing the body for a fight-or-flight response. It also helps to relax smooth muscles in the airways, making it a common treatment for severe allergic reactions and asthma attacks. Epinephrine is often administered through an injection or auto-injector device in emergency situations.
EpiPen Jr is a medical device used for emergency treatment of severe allergic reactions, also known as anaphylaxis, in children. It contains a single dose of epinephrine, a hormone that helps to reverse the symptoms of an allergic reaction and improve breathing. The EpiPen Jr is designed to be easy to use, with clear instructions and a built-in needle that automatically injects the medication into the thigh. It is a life-saving tool for children with known allergies, providing quick and effective treatment until medical help arrives.
SYMJEPI is a term that does not have a specific meaning or context. It could be a brand name, an acronym, or a random combination of letters. Without further information, it is difficult to provide a more detailed description.
