Parathyroid hormone and analogs (a synthetic form of parathyroid hormone) control the distribution of phosphate and calcium in the body. High levels of parathyroid hormone triggers transfer of calcium from the bones to the blood. It increases absorption of calcium by the intestine and increases reabsorption of calcium by the renal tubules. A low level of parathyroid hormone reduces calcium levels in the blood.
Constant high levels of parathyroid hormone cause bone resorption but sporadic administration of exogenous recombinant parathyroid hormone stimulates bone formation.
Clinically used parathyroid hormone analogs are used to build bone mass in patients who have low bone density. They are used to treat or prevent osteoporosis in men and postmenopausal women, who have fractures or are at a high risk of having fractures.
Data
Source:drugs.com
Forteo
FORTEO is a medication used to treat osteoporosis in postmenopausal women and men at high risk of fracture. It is a synthetic form of parathyroid hormone that helps to increase bone density and reduce the risk of fractures. FORTEO is typically administered as a daily injection and is prescribed for a limited duration of up to two years. It is an effective treatment option for individuals with severe osteoporosis or those who have not responded well to other osteoporosis medications.
Teriparatide is a medication used to treat osteoporosis in postmenopausal women and men at high risk of fractures. It is a synthetic form of parathyroid hormone that helps to increase bone density and reduce the risk of fractures. Teriparatide is typically administered as a daily injection and is often prescribed for individuals who have not responded well to other osteoporosis treatments.
