Angiotensin-converting enzyme inhibitors (ACE inhibitors) are a group of medicines that are mainly used to treat certain heart and kidney conditions; however, they may be used in the management of other conditions such as migraine and scleroderma.
They block the production of angiotensin II, a substance that narrows blood vessels and releases hormones such as aldosterone and norepinephrine, by inhibiting an enzyme called angiotensin converting enzyme. Angiotensin II, aldosterone, and norepinephrine all increase blood pressure and urine production by the kidneys. If levels of these three substances decrease in the body, this allows blood vessels to relax and dilate (widen), reducing both blood and kidney pressure. ACE inhibitors also increase the production of bradykinin, another substance that makes blood vessels dilate.
ACE inhibitors may be used for the treatment of the following conditions:
They may also be used for other conditions not listed here.
ACE inhibitors all work in the same way; by inhibiting the action of the angiotensin converting enzyme.
However, there are differences in their effectiveness at reducing blood pressure, their side effect profile, and their ability to prevent people from dying from a heart-related or other cause.
| Generic name | Examples of brand names |
|---|---|
| benazepril | Lotensin |
| captopril | Generic |
| enalapril | Epaned, Vasotec |
| fosinopril | Generic |
| lisinopril | Prinivil, Zestril |
| moexipril | Generic |
| perindopril | Generic |
| quinapril | Accupril |
| ramipril | Altace |
| trandolapril | Generic |
When taken at the recommended dosage, ACE inhibitors are considered safe. However, they have been associated with several serious adverse effects including:
Some of the more commonly reported side effects with ACE inhibitors include:
ACE inhibitors may be less effective at lowering blood pressure in patients of African-American descent compared to those without this ethnicity.
For a complete list of side effects, please refer to the individual drug monographs.
ACE inhibitors can also interact with several other medications (including NSAIDs and lithium). Consult your prescribing doctor before taking any other medications including those brought over the counter.
Data Source:drugs.com
Amlodipine-Benazepril is a combination medication used to treat high blood pressure. It contains two active ingredients, amlodipine and benazepril, which work together to relax blood vessels and reduce the workload on the heart. This medication is typically taken once daily and may be prescribed alongside other medications to effectively manage hypertension. It is important to follow the prescribed dosage and consult with a healthcare professional for any concerns or potential side effects.
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Benazepril HCL is a medication that belongs to the class of drugs known as ACE inhibitors. It is commonly prescribed to treat high blood pressure (hypertension) and heart failure. Benazepril HCL works by relaxing blood vessels, which helps to lower blood pressure and improve blood flow. It may also be used in combination with other medications to manage certain kidney conditions. This medication is available in tablet form and is typically taken once or twice daily, as directed by a healthcare professional.
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Benazepril-hydrochlorothiazide is a combination medication used to treat high blood pressure. It contains two active ingredients, benazepril and hydrochlorothiazide, which work together to lower blood pressure by relaxing blood vessels and reducing fluid retention. This medication is typically prescribed when lifestyle changes alone are not sufficient in controlling blood pressure. It is available in tablet form and should be taken as directed by a healthcare professional.
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Captopril is a medication used to treat high blood pressure and heart failure. It belongs to a class of drugs called ACE inhibitors, which work by relaxing blood vessels and reducing the workload on the heart. Captopril is typically taken orally and can be prescribed alone or in combination with other medications. It is important to follow the prescribed dosage and consult with a healthcare professional for proper usage and potential side effects.
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Enalapril maleate is a medication used to treat high blood pressure and heart failure. It belongs to a class of drugs called ACE inhibitors, which work by relaxing blood vessels and reducing the workload on the heart. Enalapril maleate helps to lower blood pressure and improve heart function, allowing for better circulation and oxygen supply to the body's organs. It is typically taken orally in the form of tablets and is available by prescription only. Common side effects may include dizziness, cough, and low blood pressure.
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ENALAPRIL-HYDROCHLOROTHIAZIDE is a combination medication that contains two active ingredients: enalapril, an angiotensin-converting enzyme (ACE) inhibitor, and hydrochlorothiazide, a diuretic. This medication is commonly prescribed to treat high blood pressure (hypertension) and congestive heart failure. Enalapril works by relaxing blood vessels, allowing blood to flow more easily, while hydrochlorothiazide helps the body eliminate excess salt and water, reducing fluid retention. Together, these two medications help to lower blood pressure and improve heart function.
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Fosinopril sodium is a medication used to treat high blood pressure and heart failure. It belongs to a class of drugs called ACE inhibitors, which work by relaxing blood vessels and reducing the workload on the heart. Fosinopril sodium is typically taken orally and is available in tablet form. It is important to follow the prescribed dosage and take the medication regularly for it to be effective. Common side effects may include dizziness, cough, and headache. It is important to consult with a healthcare professional before starting or stopping any medication.
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Lisinopril is a medication that belongs to a class of drugs called ACE inhibitors. It is commonly prescribed to treat high blood pressure, heart failure, and improve survival after a heart attack. Lisinopril works by relaxing blood vessels, allowing blood to flow more easily and reducing the workload on the heart. It is usually taken orally once a day and can be used alone or in combination with other medications. Common side effects may include dizziness, cough, headache, and fatigue. It is important to follow the prescribed dosage and consult a healthcare professional for any concerns or questions.
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Lisinopril-hydrochlorothiazide is a combination medication used to treat high blood pressure. It contains two active ingredients, lisinopril and hydrochlorothiazide, which work together to lower blood pressure by relaxing blood vessels and reducing fluid retention. This medication is typically prescribed when blood pressure is not adequately controlled by lisinopril alone. It is available in tablet form and is taken orally once daily. Common side effects may include dizziness, headache, and increased urination. It is important to follow the prescribed dosage and consult with a healthcare professional before starting or stopping this medication.
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MOEXIPRIL HCL is a medication that belongs to the class of drugs known as ACE inhibitors. It is commonly prescribed to treat high blood pressure and heart failure. The active ingredient in MOEXIPRIL HCL works by relaxing blood vessels, which helps to lower blood pressure and improve blood flow. This medication is typically taken orally and may be prescribed in combination with other medications for optimal results. It is important to follow the prescribed dosage and consult with a healthcare professional for any concerns or potential side effects.
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Perindopril erbumine is a medication used to treat high blood pressure and heart failure. It belongs to a class of drugs called ACE inhibitors, which work by relaxing blood vessels and reducing the workload on the heart. This medication is typically taken once daily and can help to lower blood pressure and improve symptoms of heart failure. It may also be prescribed to reduce the risk of heart attack and stroke in certain patients. Common side effects may include dizziness, cough, and headache. It is important to take this medication as prescribed and to follow up with regular blood pressure monitoring and medical appointments.
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QBRELIS is a medication that belongs to a class of drugs called ACE inhibitors. It is primarily used to treat high blood pressure and heart failure. QBRELIS works by relaxing blood vessels, allowing blood to flow more easily and reducing the workload on the heart. It may also be prescribed to prevent kidney problems in people with diabetes. QBRELIS is typically taken orally once or twice a day, with or without food. Common side effects may include dizziness, cough, and low blood pressure. It is important to follow the prescribed dosage and consult a healthcare professional for any concerns or questions.
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Quinapril is a medication that belongs to the class of drugs known as ACE inhibitors. It is primarily used to treat high blood pressure and heart failure. Quinapril works by relaxing blood vessels, which helps to lower blood pressure and improve blood flow. It may also be prescribed to prevent kidney problems in people with diabetes. This medication is typically taken orally once or twice a day, with or without food. Common side effects may include dizziness, cough, and headache. It is important to follow the prescribed dosage and consult a healthcare professional for any concerns or questions.
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Quinapril-hydrochlorothiazide is a medication that combines two active ingredients, quinapril and hydrochlorothiazide. Quinapril is an ACE inhibitor that helps to relax blood vessels and reduce blood pressure, while hydrochlorothiazide is a diuretic that helps to eliminate excess water and salt from the body. This combination medication is commonly prescribed to treat high blood pressure and congestive heart failure. It works by reducing fluid retention and improving blood flow, ultimately helping to lower blood pressure and improve overall cardiovascular health.
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Ramipril is a medication that belongs to a class of drugs called ACE inhibitors. It is commonly prescribed to treat high blood pressure and heart failure. Ramipril works by relaxing blood vessels, which helps to lower blood pressure and improve blood flow. It may also be used to reduce the risk of heart attack and stroke in certain individuals. This medication is typically taken orally and can be prescribed in different strengths. It is important to follow the dosage instructions provided by a healthcare professional and to regularly monitor blood pressure while taking Ramipril.
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Trandolapril is a medication used to treat high blood pressure and heart failure. It belongs to a class of drugs called ACE inhibitors, which work by relaxing blood vessels and reducing the workload on the heart. Trandolapril is typically taken orally once a day and can help lower blood pressure and improve heart function. It may be prescribed alone or in combination with other medications. Common side effects include dizziness, cough, and headache. It is important to follow the prescribed dosage and consult a healthcare professional for any concerns or questions.
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