PYLERA is a medication used to treat a type of bacterial infection called Helicobacter pylori. It contains a combination of three antibiotics - bismuth subcitrate potassium, metronidazole, and tetracycline - which work together to kill the bacteria and reduce symptoms such as stomach pain, ulcers, and heartburn. PYLERA is typically taken for a specific duration as prescribed by a healthcare professional and may be used in combination with other medications to effectively treat the infection.