Aldosterone receptor antagonists (also called an antimineralocorticoid, MCRA, and sometimes MRA) are a class of drugs which block the effects of aldosterone. Aldosterone is the main mineralocorticoid hormone in the body and is produced in the adrenal cortex of the adrenal gland. Aldosterone increases sodium reabsorption by the kidneys, salivary glands, sweat glands and colon. At the same time, it increases the excretion of hydrogen and potassium ions.
By blocking the effects of aldosterone, aldosterone receptor antagonists block the reabsorption of sodium, which encourages water loss. Consequently, this leads to a decrease in blood pressure and a reduction in fluid around the heart.
Aldosterone receptor antagonists may be used in the treatment of high blood pressure or heart failure. They also have a weak diuretic action.
Eplerenone is a medication used to treat high blood pressure and heart failure. It belongs to a class of drugs called mineralocorticoid receptor antagonists, which work by blocking the effects of a hormone called aldosterone. By blocking aldosterone, eplerenone helps to reduce fluid retention and lower blood pressure. It is typically taken orally in tablet form and is available by prescription only. Eplerenone may also be used in combination with other medications to effectively manage heart conditions.
Spironolactone is a medication that is primarily used to treat high blood pressure and fluid retention caused by various conditions such as heart failure, liver disease, and kidney disease. It belongs to a class of medications called aldosterone receptor antagonists, which work by blocking the effects of a hormone called aldosterone in the body. This helps to reduce the amount of water and salt retained by the kidneys, leading to decreased blood pressure and improved fluid balance. Spironolactone may also be prescribed for other off-label uses, such as treating hormonal acne and excessive hair growth in women.
Spironolactone-hydrochlorothiazide is a combination medication used to treat high blood pressure and fluid retention in the body. It contains two active ingredients, spironolactone and hydrochlorothiazide, which work together to reduce the amount of water and salt in the body, thus lowering blood pressure and preventing fluid buildup. This medication is commonly prescribed by doctors to manage conditions such as congestive heart failure, liver cirrhosis, and kidney problems. It is available in tablet form and should be taken as directed by a healthcare professional.
