Chloride channel activator agent is a locally acting agent that activates chloride channels in the intestine and increases secretion of intestinal fluid that helps in passing of the stool. It is used to treat chronic constipation especially in patients who have little or no benefit from stool softeners or laxatives.
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Source:drugs.com
Amitiza
AMITIZA is a medication used to treat chronic idiopathic constipation and irritable bowel syndrome with constipation. It works by increasing the fluid in the intestines, making it easier for stool to pass through the digestive system. AMITIZA is available in capsule form and is typically taken orally. It is prescribed by a healthcare professional and should be used as directed.
Lubiprostone is a medication used to treat chronic idiopathic constipation and irritable bowel syndrome with constipation. It works by increasing fluid secretion in the intestines, which helps to soften stool and improve bowel movements.